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Most of this research is still early-stage and often funded by the companies behind specific branded ingredients, so treat any single dramatic multiplier with healthy skepticism but the underlying mechanism is sound, established pharmaceutical science, not a marketing invention

Basically, every time that the pleasure system is kicked in in high gear, an absolutely spectacular event, you cannot be more ecstatic, there is a mirror symmetric activation of the pain system

Ukr Biokhim Zh (1999) (2005) 77(6):4650